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$200 Find cheap flights from South Carolina to Key West

This is the cheapest round-trip flight price found by a KAYAK user in the last 72 hours by searching for a flight to Key West departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Thu 6/27
Thu 7/4

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In the last 7 days travelers have searched 42,816,550 times on KAYAK, and here is why:

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Good to know

Low season

September

High season

February

Cheapest flight

$200
Best time to beat the crowds with an average 6% drop in price.
Most popular time to fly and prices are also 0% lower on average.
Flight from Myrtle Beach to Key West

FAQs for booking flights from South Carolina to Key West

  • How does KAYAK find such low prices on flights from South Carolina to Key West?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from South Carolina to Key West.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from South Carolina to Key West?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Key West from South Carolina is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from South Carolina to Key West?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Key West with an airline and back to South Carolina with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from South Carolina to Key West?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Key West from South Carolina up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from South Carolina to Key West?

Find which airlines fly direct from South Carolina to Key West, which days they fly and book direct flights.

Nonstop departures

South Carolina to Key West

Monday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Tuesday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Wednesday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Thursday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Friday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Saturday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Sunday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

See more direct flights

Nonstop returns

Key West to South Carolina

Monday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Tuesday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Wednesday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Thursday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Friday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

Saturday

Aeromexico, Air France, Alaska Airlines, +13 more

Aeromexico, Air France, +14 more

Sunday

Aeromexico, Air France, Alaska Airlines, +14 more

Aeromexico, Air France, +15 more

See more direct flights
See more direct flights

Book cheap flights from South Carolina to Key West

Recent round-trip flight deals

10/1Tue
2 stopsAmerican Airlines
8h 32mMYR-EYW
10/8Tue
1 stopAmerican Airlines
6h 14mEYW-MYR
$200
8/8Thu
1 stopAmerican Airlines
5h 05mGSP-EYW
8/12Mon
1 stopAmerican Airlines
4h 36mEYW-GSP
$217
7/11Thu
1 stopDelta
6h 04mGSP-EYW
7/16Tue
1 stopDelta
5h 21mEYW-GSP
$228
7/27Sat
1 stopDelta
6h 02mGSP-EYW
7/29Mon
1 stopDelta
5h 21mEYW-GSP
$248
7/10Wed
1 stop
13h 53mCLT-EYW
7/14Sun
1 stop
6h 46mEYW-CLT
$318
7/10Wed
2 stops
16h 13mCLT-EYW
7/14Sun
1 stop
6h 46mEYW-CLT
$340
7/3Wed
2 stopsAllegiant Air
16h 16mGSP-EYW
7/8Mon
1 stopAllegiant Air
4h 20mEYW-GSP
$398
6/24Mon
1 stopAllegiant Air
6h 41mSAV-EYW
7/1Mon
1 stopAllegiant Air
5h 41mEYW-SAV
$418
8/17Sat
2 stopsUnited Airlines
12h 35mCLT-EYW
8/23Fri
2 stopsUnited Airlines
17h 59mEYW-CLT
$421
11/16Sat
2 stopsUnited Airlines
23h 32mCLT-EYW
11/19Tue
2 stopsUnited Airlines
26h 34mEYW-CLT
$436

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Recent one-way flight deals

7/3Wed
2 stopsAllegiant Air
16h 16mGSP-EYW
$238
9/20Fri
1 stopAmerican Airlines
6h 48mGSP-EYW
$258
6/25Tue
1 stopAmerican Airlines
7h 30mCLT-EYW
$258
9/20Fri
2 stopsAmerican Airlines
8h 34mGSP-EYW
$263
11/24Sun
1 stopDelta
5h 08mGSP-EYW
$281
6/25Tue
2 stopsUnited Airlines
26h 15mCLT-EYW
$283
6/12Wed
1 stopUnited Airlines
8h 04mCLT-EYW
$284
6/11Tue
2 stopsUnited Airlines
32h 00mGSP-EYW
$292
6/11Tue
1 stopAmerican Airlines
7h 00mGSP-EYW
$293
6/22Sat
1 stopDelta
5h 08mCLT-EYW
$323

Search by stops

Search by airline

Search by price

Last minute flights from South Carolina to Key West

Last minute flight, train and bus deals

5/29Wed
multi-stopAmerican Airlines
4h 16mGSP-EYW
6/1Sat
multi-stopAmerican Airlines
6h 41mEYW-GSP
$335
5/29Wed
multi-stopAmerican Airlines
8h 38mGSP-EYW
6/1Sat
multi-stopAmerican Airlines
6h 41mEYW-GSP
$340
5/31Fri
multi-stopAmerican Airlines
4h 44mMYR-EYW
6/3Mon
multi-stopAmerican Airlines
4h 04mEYW-MYR
$357
5/31Fri
multi-stopAmerican Airlines
7h 04mMYR-EYW
6/3Mon
multi-stopAmerican Airlines
6h 26mEYW-MYR
$362
5/31Fri
multi-stopAmerican Airlines
9h 57mMYR-EYW
6/3Mon
multi-stopAmerican Airlines
8h 07mEYW-MYR
$367
5/31Fri
multi-stop
10h 20mCHS-EYW
6/2Sun
multi-stop
25h 47mEYW-CHS
$533
6/1Sat
multi-stopUnited Airlines
8h 04mCLT-EYW
6/5Wed
multi-stopUnited Airlines
6h 17mEYW-CLT
$576
6/1Sat
multi-stopUnited Airlines
8h 04mCLT-EYW
6/5Wed
multi-stopUnited Airlines
7h 39mEYW-CLT
$581
6/2Sun
multi-stopDelta
4h 58mGSP-EYW
6/9Sun
multi-stopDelta
6h 24mEYW-GSP
$623
6/1Sat
multi-stopDelta
7h 00mCLT-EYW
6/8Sat
multi-stopDelta
5h 54mEYW-CLT
$767

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Flights to Key West

Destination:

Key West (EYW)United States

Return flight deals:

Key West - South Carolina

Cabin classes: