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$133 Find cheap flights from Iowa to Panama City, Florida

This is the cheapest one-way flight price found by a KAYAK user in the last 72 hours by searching for a flight to Panama City departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
1 adult
0 bags
Sat 6/15
Sat 6/22

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In the last 7 days travelers have searched 42,211,976 times on KAYAK, and here is why:

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Good to know

Low season

January

High season

June

Cheapest flight

$133
Best time to beat the crowds with an average 11% drop in price.
Most popular time to fly with an average 4% increase in price.
Flight from Des Moines to Panama City

FAQs for booking flights from Iowa to Panama City

  • How does KAYAK find such low prices on flights from Iowa to Panama City?

    KAYAK is a travel search engine. That means we look across the web to find the best prices we can find for our users. With over 2 billion flight queries processed yearly, we are able to display a variety of prices and options on flights from Iowa to Panama City.

  • How does KAYAK's flight Price Forecast tool help me choose the right time to buy my flight ticket from Iowa to Panama City?

    KAYAK’s flight Price Forecast tool uses historical data to determine whether the price for a flight to Panama City from Iowa is likely to change within 7 days, so travelers know whether to wait or book now.

  • What is the Hacker Fare option on flights from Iowa to Panama City?

    Hacker Fares allow you to combine one-way tickets in order to save you money over a traditional round-trip ticket. You could then fly to Panama City with an airline and back to Iowa with another airline.

  • What is KAYAK's "flexible dates" feature and why should I care when looking for a flight from Iowa to Panama City?

    Sometimes travel dates aren't set in stone. If your preferred travel dates have some wiggle room, flexible dates will show you all the options when flying to Panama City from Iowa up to 3 days before/after your preferred dates. You can then pick the flights that suit you best.

See more FAQs

Prefer to fly non-stop from Iowa to Panama City?

Find which airlines fly direct from Iowa to NW Florida Beaches, which days they fly and book direct flights.

Nonstop departures

Iowa to Panama City NW Florida Beaches

Monday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Tuesday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Wednesday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Thursday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Friday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Saturday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Sunday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

See more direct flights

Nonstop returns

Panama City NW Florida Beaches to Iowa

Monday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Tuesday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Wednesday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Thursday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Friday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Saturday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

Sunday

Aeromexico, Air France, American Airlines, +8 more

Aeromexico, Air France, +9 more

See more direct flights
See more direct flights

Book cheap flights from Iowa to Panama City

Recent round-trip flight deals

8/31Sat
1 stopAmerican Airlines
5h 33mDSM-ECP
9/7Sat
1 stopAmerican Airlines
4h 40mECP-DSM
$265
10/1Tue
1 stopDelta
4h 02mDSM-ECP
10/2Wed
1 stopDelta
4h 21mECP-DSM
$266
8/31Sat
2 stopsDelta
6h 44mDSM-ECP
9/7Sat
1 stopDelta
4h 14mECP-DSM
$271
8/31Sat
2 stopsDelta
6h 44mDSM-ECP
9/7Sat
2 stopsDelta
8h 04mECP-DSM
$276
8/1Thu
1 stopDelta
4h 32mMLI-ECP
8/7Wed
1 stopDelta
3h 58mECP-MLI
$288
9/16Mon
1 stopAmerican Airlines
5h 07mOMA-ECP
9/20Fri
1 stopAmerican Airlines
6h 57mECP-OMA
$295
7/3Wed
1 stopDelta
6h 40mDSM-ECP
7/8Mon
1 stopDelta
6h 09mECP-DSM
$296
5/26Sun
2 stopsUnited Airlines
11h 17mCID-ECP
5/29Wed
2 stopsUnited Airlines
13h 41mECP-CID
$474
6/2Sun
1 stopUnited Airlines
5h 21mOMA-ECP
6/8Sat
2 stopsUnited Airlines
13h 41mECP-OMA
$523
6/30Sun
1 stopUnited Airlines
5h 51mDSM-ECP
7/6Sat
1 stopUnited Airlines
5h 08mECP-DSM
$527

Search by stops

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Recent one-way flight deals

10/1Tue
1 stopDelta
5h 21mDSM-ECP
$133
5/22Wed
1 stopDelta
4h 44mDSM-ECP
$195
10/1Tue
2 stopsDelta
10h 19mDSM-ECP
$224
5/22Wed
2 stopsDelta
8h 53mDSM-ECP
$225
5/22Wed
1 stopDelta
4h 17mCID-ECP
$353
5/22Wed
2 stopsUnited Airlines
7h 41mCID-ECP
$358

Search by stops

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Last minute flights from Iowa to Panama City

Last minute flight, train and bus deals

5/21Tue
multi-stopAmerican Airlines
7h 20mDSM-ECP
5/28Tue
multi-stopAmerican Airlines
7h 11mECP-DSM
$605
5/21Tue
multi-stopAmerican Airlines
5h 18mDSM-ECP
5/28Tue
multi-stopAmerican Airlines
9h 35mECP-DSM
$610
5/21Tue
multi-stopAmerican Airlines
9h 00mDSM-ECP
5/28Tue
multi-stopAmerican Airlines
9h 35mECP-DSM
$617

Search by stops

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Flights to Panama City

Destination:

Panama City (ECP)United States

Return flight deals:

Panama City - Iowa

Cabin classes: